Discogenic back pain is the most common type of back pain and accounts for around a third of all cases of lower back pain. Studies suggest that degeneration of a disc and might be the result of an injury and subsequent repair of annulus fibrosus. Discogenic back pain can be classified into two types: Annular disruption-induced low back pain and internal endplate disruption induced low back pain. Treatment can relieve the symptoms but can not restore the disc’s structure although recently there has been growing interest in the medical research field in developing strategies that aim to repair discs biologically.